Silybum marianum (Thistle) extract, silymarine is a compound that contains silybin, silychristin and silydianin as main components. Silymarine has very positive effect on treatment of cirrhosis that occurs by toxic effects of chemicals or viruses for chronic use of alcohol. It helps to protect liver and provide therapeutic efficacy by inhibiting access of toxins to liver and toxins connected out of cell membrane of liver. Silymarine affects by increasing ribosomal protein synthesis and liver’s ability to renew itself.

Artichoke leaf extract is used for renewal of liver cells of which function decreases by effects such as drug use, smoking, alcohol, as a liver protective and treatment of liver failure. Artichoke preparations are used very extensively for problems of bloating and indigestion. Artichoke leaf extract provides proper functioning of gall bladder by increasing bile production of liver and decreases amounts of cholesterol, LDL and triglyceride by helping digestion.

Dandelion root and extract is used for problems of liver and gall bladder. It helps digestion with its diuretic effect while making detox.

Grape seed extract has a wide range of pharmacological activity with its antioxidant, anti-inflammatory, antimicrobial, cardio protective, hepatoprotective, neuroprotective effects. Besides cardiovascular protective and chemopreventive effects of the other phytochemicals with proantocianidins found in grape seed, it is shown that grape has effective compositions on Alzheimer disease. with many clinical investigations of grape, it is examined with the that thrombocyt aggregation is decreased, endothelial functions are recovered, blood pressure is decreased and level of atheroscleorotic and athereotrombotic risk markers is got better.